NMR


NMR takes advantage of the fact that some nuclei have access to two or more energy levels when they are subjected to an external magnetic field. The experiment induces transitions of the nuclei between these energy levels.

Number and spacing of the energy levels

The number of energy levels in the presence of an applied magnetic field is 2I+1, where I is the nuclear spin quantum number.

Chemical Shift

The local field sensed by a nucleus is dominated by muH0. However, it can be modified slightly by shielding by nearby electrons. This slight affect is exploited in nmr spectroscopy. The modification is proportional to muH0, but this proportionality is removed from the data when the frequencies are converted to chemical shifts, d, using a standard substance.

d = (Hreference - Hsample)/Hreference

The protons in tetramethylsilane (TMS) are frequently used as a reference in proton nmr. Since the effect is small, d is usually quoted in parts per million, ppm. The range covered depends on the type of nucleus examined, being larger for 13C (~600 ppm) than for 1H (~10 ppm). With proton nmr, the areas under the peaks in the spectrum are proportional to the number of protons in a given magnetic environment. Therefore ethanol, at low resolution, shows three peaks, with areas in the ratio of 3:2:1, for the protons in the methyl:methylene:hydroxyl groups. Ring currents in aromatic rings (such as those found in polystyrene) can produce important changes in d for protons closeby, with the size of the effect depending on distance from the aromatic ring, and orientation with respect to the normal to the plane of that ring.

Spin-Spin Interactions

When ethanol is examined at higher resolution, fine structure is revealed in the methyl and methylene peaks.

The splittings arise from interaction of the spins on hydrogens bonded to neighboring carbon atoms. The multiplicity from n hydrogen atoms is n + 1, with the intensities being 1:1 for doublets, 1:2:1 for triplets, 1:3:3:1 for quadruplets, etc. The spacing, determined by the spin-sping coupling constant J, is independent of H0. The value of J in the fragment H-C-C-H depends on the torsion angle at the C-C bond, but this dependence is not apparent in ethanol, because rotation about this bond is rapid on the nmr time scale. If rotation about the C-C` bond is slow (which can occur if this bond is incorporated into a ring), then measurement of the size of J gives information about the conformation at that bond.

Some distinguishing features of 13C nmr

For a recent brief review of nmr of polymers, see Tonelli Physical Properties of Polymers Handbook Mark, J. E., Ed., American Institute of Physics, 1996, p 271. An excellent book on nmr is Bovey, F. A. Nuclear Magnetic Resonance Spectroscopy Academic Press, New York, 1988. The technique can be used to determine tacticity and sequence isomerization.

A good online source for more extensive fundamental information on nmr can be found under Basics of NMR at the web site maintained by Prof. Hornak.

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October 8, 1999
Wayne L. Mattice: wlm@polymer.uakron.edu