Lyn G. Muñoz Robledo
Project Objectives: The synthesis and characterization of poly styrene-poly(isobutylene)-polystyrene (PS-PIB-PS) block copolymer, commercially known as (SIBS) has long been known. This polymer is used to sequester Paclitaxel® in one of the most successful drug-eluting stents on the markert used to treat blockages of the coronary arteries. A subsequent generation of SIBS has now been created which is highly branched or arborescent (isobutylene)-Styrene (IB-St), called arbIB-St. This new generation of polymer may have superior biocompatibility properties compared to SIBS. The objective of my research is characterize the physical properties of the arbIB-St and to determine the impact of this arborescent configuration compared to original SIBS upon cell attachment and proliferation.